1185004-43-6

1185004-43-6 structure
1185004-43-6 structure
  • Name: Sultopride-d5
  • Chemical Name: Sultopride-d5
  • CAS Number: 1185004-43-6
  • Molecular Formula: C17H21D5N2O4S
  • Molecular Weight: 359.50
  • Catalog: Signaling Pathways GPCR/G Protein Dopamine Receptor
  • Create Date: 2021-11-25 20:31:34
  • Modify Date: 2024-01-10 21:21:42
  • Sultopride-d5 (LIN-1418-d5) is the deuterium labeled Sultopride. Sultopride (LIN-1418) is a selective antagonist of dopamine D2 receptor[1][2].

Name Sultopride-d5
Description Sultopride-d5 (LIN-1418-d5) is the deuterium labeled Sultopride. Sultopride (LIN-1418) is a selective antagonist of dopamine D2 receptor[1][2].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

[2]. Moriuchi K, et al. Differences in effects of sultopride and sulpiride on dopamine turnover in rat brain. Neurochem Res. 1995 Jan;20(1):95-9.

Molecular Formula C17H21D5N2O4S
Molecular Weight 359.50