627052-25-9
627052-25-9 structure
- Name: SQ609
- Chemical Name: SQ609
- CAS Number: 627052-25-9
- Molecular Formula: C22H38N2O
- Molecular Weight: 346.55
- Catalog: Signaling Pathways Anti-infection Bacterial
- Create Date: 2021-10-23 13:51:01
- Modify Date: 2024-01-13 20:40:04
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SQ609 is a lead compound from a library of dipiperidines. SQ609 inhibits more than 90% of intracellular bacterial growth at 4μg/ml and is toxic to these cells. SQ609 displays a potent antitubercular activity [1].
| Name | SQ609 |
|---|
| Description | SQ609 is a lead compound from a library of dipiperidines. SQ609 inhibits more than 90% of intracellular bacterial growth at 4μg/ml and is toxic to these cells. SQ609 displays a potent antitubercular activity [1]. |
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| Related Catalog | |
| In Vitro | In Mtb-infected macrophages in vitro, SQ609 inhibits more than 90% of intracellular bacterial growth at 4μg/ml and is toxic to these cells[1]. |
| In Vivo | SQ609 (10 mg/kg; intravenous injection) completely prevents weight loss in the Mtb-infected animals and prolongs the therapeutic effect following drug withdrawal for another 10-15 days[1]. Animal Model: TB susceptible mice (C3H/He)[1] Dosage: 10 mg/kg Administration: I.v. Result: Prevented weight loss in the Mtb-infected animals and prolonged the therapeutic effect following drug withdrawal for another 10-15 days. |
| References |
| Molecular Formula | C22H38N2O |
|---|---|
| Molecular Weight | 346.55 |