1217774-40-7

1217774-40-7 structure

Name: Milnacipran-d10 hydrochloride
Chemical Name: Milnacipran-d10 hydrochloride
CAS Number: 1217774-40-7
Molecular Formula: C₁₅H₁₃D₁₀ClN₂O
Molecular Weight: 292.87
Catalog: Signaling Pathways Neuronal Signaling Serotonin Transporter
Create Date: 2021-10-07 17:55:03
Modify Date: 2024-01-30 15:44:19
Milnacipran-d10 hydrochloride is the deuterium labeled Milnacipran hydrochloride. Milnacipran hydrochloride is a serotonin-norepinephrine reuptake inhibitor (SNRI) used in the clinical treatment of fibromyalgia[1][2].

Name	Milnacipran-d10 hydrochloride

Description	Milnacipran-d10 hydrochloride is the deuterium labeled Milnacipran hydrochloride. Milnacipran hydrochloride is a serotonin-norepinephrine reuptake inhibitor (SNRI) used in the clinical treatment of fibromyalgia[1][2].
Related Catalog	Research Areas >> Neurological Disease Signaling Pathways >> Neuronal Signaling >> Serotonin Transporter
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Moret C, et al. Biochemical profile of midalcipran (F 2207), 1-phenyl-1-diethyl-aminocarbonyl-2-aminomethyl-cyclopropane (Z) hydrochloride, a potential fourth generation antidepressant drug. Neuropharmacology. 1985 Dec;24(12):1211-9. [3]. Briley M, et al. Preclinical pharmacology of milnacipran. Int Clin Psychopharmacol. 1996 Sep;11 Suppl 4:9-14.

Molecular Formula	C₁₅H₁₃D₁₀ClN₂O
Molecular Weight	292.87