1346598-82-0

1346598-82-0 structure
1346598-82-0 structure
  • Name: Ioxilan-d4
  • Chemical Name: Ioxilan-d4
  • CAS Number: 1346598-82-0
  • Molecular Formula: C18H20D4I3N3O8
  • Molecular Weight: 795.14
  • Catalog: Research Areas Others
  • Create Date: 2021-10-19 18:14:32
  • Modify Date: 2025-08-25 18:54:04
  • Ioxilan-d4 is the deuterium labeled Ioxilan. Ioxilan is a low-osmolar, nonionic and tri-iodinated diagnostic contrast agent. Ioxilan is also an X-ray contrast agent for excretory urography and contrast enhanced computed tomographic (CECT) imaging of the head and body. Intravascular injection results in opacification of vessels in the path of flow of the contrast medium, permitting radiographic visualization of the internal structures of the human body until significant hemodilution occurs[1][2][3].

Name Ioxilan-d4
Description Ioxilan-d4 is the deuterium labeled Ioxilan. Ioxilan is a low-osmolar, nonionic and tri-iodinated diagnostic contrast agent. Ioxilan is also an X-ray contrast agent for excretory urography and contrast enhanced computed tomographic (CECT) imaging of the head and body. Intravascular injection results in opacification of vessels in the path of flow of the contrast medium, permitting radiographic visualization of the internal structures of the human body until significant hemodilution occurs[1][2][3].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

[2]. Cheng KT. Ioxilan carbonate particles. National Center for Biotechnology Information (US); 2004-2013. 2007 Sep 1.

[3]. Chow SL, et al. Effect of iodixanol and ioxilan on QT interval and renal function in patients with systolic heart failure. Int J Cardiol. 2012 Jan 12;154(1):17-21.

[4]. Nonionic Contrast Agents.

Molecular Formula C18H20D4I3N3O8
Molecular Weight 795.14
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