2104030-82-0

2104030-82-0 structure

Name: 6-Benzyl-3-(3-(thiazol-5-ylmethoxy)phenyl)-3,4-dihydropyrido[4,3-d]pyrimidine-2,7(1H,6H)-dione
Chemical Name: Brr2-IN-3
CAS Number: 2104030-82-0
Molecular Formula: C₂₄H₂₀N₄O₃S
Molecular Weight: 444.51
Catalog: Research Areas Others
Create Date: 2021-09-13 17:17:16
Modify Date: 2025-08-25 16:38:21
Brr2-IN-3 is a potent and selective Brr2 helicase allosteric Inhibitor. Brr2-IN-3 inhibits helicase activity in dose-dependent manner with an IC50 value of 1.3 μM[1].

Name	Brr2-IN-3

Description	Brr2-IN-3 is a potent and selective Brr2 helicase allosteric Inhibitor. Brr2-IN-3 inhibits helicase activity in dose-dependent manner with an IC50 value of 1.3 μM[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
Target	IC50: 1.3 μM (Brr2)[1]
References	[1]. Iwatani-Yoshihara M, et al. Discovery of Allosteric Inhibitors Targeting the Spliceosomal RNA Helicase Brr2. J Med Chem. 2017;60(13):5759-5771.

Hazard Codes	Xn