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2211981-77-8

2211981-77-8 structure

2211981-77-8 structure

Name: Atuzaginstat hydrochloride
Chemical Name: Atuzaginstat hydrochloride
CAS Number: 2211981-77-8
Molecular Formula: C₁₉H₂₆ClF₃N₂O₃
Molecular Weight: 422.87
Catalog: Signaling Pathways Anti-infection Bacterial
Create Date: 2021-09-12 19:15:48
Modify Date: 2025-09-07 02:02:22
Atuzaginstat (COR388) hydrochloride is an effective small-molecule bacterial protease lysine gingipain inhibitor and can be used for Alzheimer's disease research[1][2].

Name	Atuzaginstat hydrochloride

Description	Atuzaginstat (COR388) hydrochloride is an effective small-molecule bacterial protease lysine gingipain inhibitor and can be used for Alzheimer's disease research[1][2].
Related Catalog	Research Areas >> Neurological Disease Signaling Pathways >> Anti-infection >> Bacterial
Target	Lysine gingipain[1]
References	[1]. Arastu-Kapur, S., et al. 676 PD-L1 is induced by the periodontal pathogen porphyromonas gingivalis and can be blocked by small molecule gingipain inhibitors, including atuzaginstat. Journal for Immuno Therapy of Cancer. 2020; 8(Suppl 3): A715-A715. [2]. Cortexyme Presents an Update and Baseline Data from the Phase 2/3 GAIN Trial of Atuzaginstat at CTAD 2020, the Clinical Trials on Alzheimer’s Disease Conference.

Molecular Formula	C₁₉H₂₆ClF₃N₂O₃
Molecular Weight	422.87

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