161099-37-2

161099-37-2 structure

Name: Glicoricone
Chemical Name: Glicoricone
CAS Number: 161099-37-2
Molecular Formula: C₂₁H₂₀O₆
Molecular Weight: 368.38
Catalog: Signaling Pathways Neuronal Signaling Monoamine Oxidase
Create Date: 2021-09-16 13:14:24
Modify Date: 2025-08-25 17:40:01
Glicoricone, a phenolic compound, is isolated from a species of licorice. Glicoricone is an inhibitor of monoamine oxidase (MAO), with an IC50 of 140 μM. Glicoricone binds to estrogen receptor (ER) and shows estrogen antagonist activity[1][2].

Name	Glicoricone

Description	Glicoricone, a phenolic compound, is isolated from a species of licorice. Glicoricone is an inhibitor of monoamine oxidase (MAO), with an IC50 of 140 μM. Glicoricone binds to estrogen receptor (ER) and shows estrogen antagonist activity[1][2].
Related Catalog	Signaling Pathways >> Others >> Estrogen Receptor/ERR Signaling Pathways >> Neuronal Signaling >> Monoamine Oxidase Research Areas >> Metabolic Disease
Target	IC50: 140 μM (monoamine oxidase)[1]
References	[1]. Hatano T, et, al. Phenolic constituents of licorice. III. Structures of glicoricone and licofuranone, and inhibitory effects of licorice constituents on monoamine oxidase. Chem Pharm Bull (Tokyo). 1991 May;39(5):1238-43. [2]. Boonmuen N, et, al. Licorice root components in dietary supplements are selective estrogen receptor modulators with a spectrum of estrogenic and anti-estrogenic activities. Steroids. 2016 Jan;105:42-9.

Molecular Formula	C₂₁H₂₀O₆
Molecular Weight	368.38