CHEMICAL IDENTIFICATION
-
RTECS NUMBER :
-
KD7875000
-
CHEMICAL NAME :
-
Equilin, benzoate
-
CAS REGISTRY NUMBER :
-
6030-80-4
-
BEILSTEIN REFERENCE NO. :
-
3172244
-
LAST UPDATED :
-
199612
-
DATA ITEMS CITED :
-
3
-
MOLECULAR FORMULA :
-
C25-H24-O3
-
MOLECULAR WEIGHT :
-
372.49
-
WISWESSER LINE NOTATION :
-
L E5 B666 FV JUTTT&J E1 DOVR
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
-
TYPE OF TEST :
-
TDLo - Lowest published toxic dose
-
ROUTE OF EXPOSURE :
-
Subcutaneous
-
SPECIES OBSERVED :
-
Rodent - mouse
-
DOSE/DURATION :
-
96 mg/kg/48W-I
-
TOXIC EFFECTS :
-
Tumorigenic - neoplastic by RTECS criteria Blood - lymphoma, including Hodgkin's disease Skin and Appendages - tumors
-
REFERENCE :
-
ZEKBAI Zeitschrift fuer Krebsforschung. (Berlin, Fed. Rep. Ger.) V.1-75, 1903-71. For publisher information, see JCROD7. Volume(issue)/page/year: 56,482,1949
-
TYPE OF TEST :
-
TDLo - Lowest published toxic dose
-
ROUTE OF EXPOSURE :
-
Parenteral
-
SPECIES OBSERVED :
-
Rodent - mouse
-
DOSE/DURATION :
-
42 mg/kg/21W-I
-
TOXIC EFFECTS :
-
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Skin and Appendages - tumors
-
REFERENCE :
-
CRSBAW Comptes Rendus des Seances de la Societe de Biologie et de Ses Filiales. (SPPIF, B.P.22, F-41353 Vineuil, France) V.1- 1849- Volume(issue)/page/year: 122,183,1936
-
TYPE OF TEST :
-
TD - Toxic dose (other than lowest)
-
ROUTE OF EXPOSURE :
-
Subcutaneous
-
SPECIES OBSERVED :
-
Rodent - mouse
-
DOSE/DURATION :
-
148 mg/kg/37W-I
-
TOXIC EFFECTS :
-
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Skin and Appendages - tumors Reproductive - Tumorigenic effects - uterine tumors
-
REFERENCE :
-
YJBMAU Yale Journal of Biology and Medicine. (333 Cedar St., New Haven, CT 06510) V.1- 1928- Volume(issue)/page/year: 12,213,1939
|
