146724-82-5
146724-82-5 structure
- Name: NOC-5
- Chemical Name: 3-[2-Hydroxy-1-(1-Methylethyl)-2-Nitrosohydrazino]-1-Propanamine Discontinued
- CAS Number: 146724-82-5
- Molecular Formula: C6H16N4O2
- Molecular Weight: 176.217
- Catalog: Research Areas Cancer
- Create Date: 2018-12-24 15:21:24
- Modify Date: 2024-01-05 18:23:16
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NOC-5 is a diazeniumdiolate compound that belongs to the same family of NO donors[1].
| Name | 3-[2-Hydroxy-1-(1-Methylethyl)-2-Nitrosohydrazino]-1-Propanamine Discontinued |
|---|---|
| Synonyms |
N-[3-aminopropyl(propan-2-yl)amino]-N-hydroxynitrous amide
3-(Aminopropyl)-1-hydroxy-3-isopropyl-2-oxo-1-triazene 1-(3-Aminopropyl)-2-hydroxy-1-isopropyl-3-oxotriazane 1-Propanamine, 3-[2-hydroxy-1-(1-methylethyl)-3-oxotriazanyl]- 3-(2-Hydroxy-1-(1-methylethyl)-2-nitrosohydrazino)-1-propanamine MFCD00274389 |
| Description | NOC-5 is a diazeniumdiolate compound that belongs to the same family of NO donors[1]. |
|---|---|
| Related Catalog | |
| In Vitro | NOC-5 (5-20 μM) in PBS led to a rapid increase in NO release on day one[1]. NOC-5 (100 μM, 24 h) activates only caspase-3; an increase in caspase-3 activity occurred after NO donor treatment: 1.62 (1.57-1.66) (P < 0.05). NOC-5 has pro-apoptotic action in Jurkat cells, but at the same time increased the level of anti-apoptotic proteins[2]. |
| References |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 270.1±42.0 °C at 760 mmHg |
| Molecular Formula | C6H16N4O2 |
| Molecular Weight | 176.217 |
| Flash Point | 117.2±27.9 °C |
| Exact Mass | 176.127319 |
| PSA | 90.60000 |
| LogP | 0.02 |
| Vapour Pressure | 0.0±1.2 mmHg at 25°C |
| Index of Refraction | 1.525 |