DC Chemicals Limited
China
Product Name: 10Z-Hymenialdisine
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

82005-12-7

82005-12-7 structure

82005-12-7 structure

Name: 10Z-Hymenialdisine
Chemical Name: 10z-hymenialdisine
CAS Number: 82005-12-7
Molecular Formula: C₁₁H₁₀BrN₅O₂
Molecular Weight: 324.13300
Create Date: 2018-07-30 12:11:15
Modify Date: 2024-01-07 11:57:45
10Z-Hymenialdisine ((Z)-Hymenialdisine) is a natural bioactive pyrrole alkaloid. 10Z-Hymenialdisine is a pan kinase inhibitor, and has anticancer activities[1].

Name	10z-hymenialdisine
Synonyms	Hymenialdisine

Description	10Z-Hymenialdisine ((Z)-Hymenialdisine) is a natural bioactive pyrrole alkaloid. 10Z-Hymenialdisine is a pan kinase inhibitor, and has anticancer activities[1].
Related Catalog	Signaling Pathways >> Epigenetics >> AMPK Research Areas >> Cancer Signaling Pathways >> Protein Tyrosine Kinase/RTK >> PDGFR Signaling Pathways >> PI3K/Akt/mTOR >> AMPK Signaling Pathways >> Protein Tyrosine Kinase/RTK >> VEGFR
In Vitro	10Z-Hymenialdisine displays a moderate effect on (ARK5, VEGFR-2, SAK and PDGFR) protein kinases. 10Z-Hymenialdisine shows a potent inhibition of RAF/MEK-1/MAPK cascade with an IC50 value of 6 nM[1].
References	[1]. Ashraf N E Hamed, et al. Bioactive pyrrole alkaloids isolated from the Red Sea: marine sponge Stylissa carteri. Z Naturforsch C J Biosci. 2018 Apr 25;73(5-6):199-210.

Density	2.2 g/cm3
Melting Point	160-164ºC
Molecular Formula	C₁₁H₁₀BrN₅O₂
Molecular Weight	324.13300
Exact Mass	323.00200
PSA	112.37000
LogP	0.85980
Index of Refraction	1.911

Precursor 0
DownStream 1
96562-96-8