- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: 5-Maleimidovaleric acid
- Price: Check
- Purity: 98.0%
- Stocking Period: 10 Day
- Contact: Yang
- Email: sales@echemcloud.com
- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: 5-Maleimidovaleric acid
- Price: ￥498.0/25mg ￥1198.0/100mg
- Purity: 98.0%
- Stocking Period: 2 Day
- Contact: Liu jia
- Email: 2130147988@qq.com
- DC Chemicals Limited
- China
- Product Name: 5-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)pentanoic acid
- Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
- Purity: 98.0%
- Stocking Period: 3 Day
- Contact: Tony Cao
- Email: sales@dcchemicals.com
- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: 5-MALEIMIDOVALERIC ACID(DMVA)
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Ms Wang
- Email: enquiry@dycnchem.com
- Shanghai Amole Biotechnology Co., Ltd.
- China
- Product Name: 5-Maleimidovaleric acid
- Price: ￥Inquiry/100mg ￥Inquiry/1g ￥Inquiry/250mg ￥Inquiry/5g
- Purity: 97.0%
- Stocking Period: Inquiry
- Contact: Xiyao Wang
- Email: 3623107365@qq.com
57078-99-6
57078-99-6 structure
- Name: 5-Maleimidovaleric acid
- Chemical Name: 5-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)pentanoic acid
- CAS Number: 57078-99-6
- Molecular Formula: C9H11NO4
- Molecular Weight: 197.188
- Catalog: Signaling Pathways Antibody-drug Conjugate ADC Linker
- Create Date: 2018-04-27 08:00:00
- Modify Date: 2025-08-24 19:41:23
-
5-Maleimidovaleric acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
| Name | 5-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)pentanoic acid |
|---|---|
| Synonyms |
5-(2,5-dioxopyrrol-1-yl)pentanoic acid
5-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)pentanoic acid 1H-Pyrrole-1-pentanoic acid, 2,5-dihydro-2,5-dioxo- 5-Maleimidovaleric acid |
| Description | 5-Maleimidovaleric acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. |
|---|---|
| Related Catalog | |
| Target |
Cleavable |
| In Vitro | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1]. |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 400.7±28.0 °C at 760 mmHg |
| Molecular Formula | C9H11NO4 |
| Molecular Weight | 197.188 |
| Flash Point | 196.2±24.0 °C |
| Exact Mass | 197.068802 |
| PSA | 74.68000 |
| LogP | 0.56 |
| Vapour Pressure | 0.0±2.0 mmHg at 25°C |
| Index of Refraction | 1.544 |
| Hazard Codes | Xi |
|---|---|
| HS Code | 2925190090 |
|
~60%
57078-99-6 |
| Literature: De Figueiredo, Renata Marcia; Oczipka, Philipp; Froehlich, Roland; Christmann, Mathias Synthesis, 2008 , # 8 p. 1316 - 1318 |
| HS Code | 2925190090 |
|---|---|
| Summary | 2925190090 other imides and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0% |