83-72-7

DATA ITEMS CITED :

6

MOLECULAR FORMULA :

C10-H6-O3

MOLECULAR WEIGHT :

174.16

WISWESSER LINE NOTATION :

L66 BV EVJ CQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intraperitoneal

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

100 mg/kg

TOXIC EFFECTS :

Tumorigenic - active as anti-cancer agent

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

522 mg/kg/6D-I

TOXIC EFFECTS :

Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis) Blood - changes in spleen Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - dehydrogenases

MUTATION DATA

TEST SYSTEM :

Rodent - mouse

DOSE/DURATION :

50 mg/kg

REFERENCE :

MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 343,61,1995 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X9568 No. of Facilities: 227 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 2271 (estimated) No. of Female Employees: 1817 (estimated)