2138440-81-8

2138440-81-8 structure

Name: Pomalidomide-PEG4-COOH
Chemical Name: Pomalidomide-PEG4-CO2H
CAS Number: 2138440-81-8
Molecular Formula: C₂₄H₃₁N₃O₁₀
Molecular Weight: 521.517
Catalog: Signaling Pathways PROTAC Ligand for E3 Ligase
Create Date: 2021-09-10 22:52:10
Modify Date: 2024-04-06 21:08:41
Pomalidomide-PEG4-COOH is a E3 ligase ligand-linker conjugate. Pomalidomide-PEG4-COOH contains the Pomalidomide based cereblon ligand and 4-unit PEG linker used in PROTAC technology (extracted from patent WO2017184995A1)[1].

Name	Pomalidomide-PEG4-CO2H
Synonyms	3,6,9,12-Tetraoxapentadecan-15-oic acid, 1-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]- 1-{[2-(2,6-Dioxo-3-piperidinyl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]amino}-3,6,9,12-tetraoxapentadecan-15-oic acid

Description	Pomalidomide-PEG4-COOH is a E3 ligase ligand-linker conjugate. Pomalidomide-PEG4-COOH contains the Pomalidomide based cereblon ligand and 4-unit PEG linker used in PROTAC technology (extracted from patent WO2017184995A1)[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> PROTAC >> Ligand for E3 Ligase
References	[1]. Guangrong Zheng, et al.Compounds that induce degradation of anti-apoptotic bcl-2 family proteins and the uses thereof. Patent WO2017184995A1.