2115742-03-3

2115742-03-3 structure
2115742-03-3 structure
  • Name: NHWD-870
  • Chemical Name: NHWD-870
  • CAS Number: 2115742-03-3
  • Molecular Formula: C29H29N7O
  • Molecular Weight: 491.59
  • Create Date: 2021-09-11 19:59:32
  • Modify Date: 2024-01-05 19:50:52
  • NHWD-870 is a potent, orally active and selective BET family bromodomain and only binds bromodomains of BRD2, BRD3, BRD4 (IC50=2.7 nM), and BRDT. NHWD-870 has potent tumor suppressive efficacies and suppresses cancer cell-macrophage interaction. NHWD-870 increases tumor apoptosis and inhibits tumor proliferation.

Name NHWD-870
Description NHWD-870 is a potent, orally active and selective BET family bromodomain and only binds bromodomains of BRD2, BRD3, BRD4 (IC50=2.7 nM), and BRDT. NHWD-870 has potent tumor suppressive efficacies and suppresses cancer cell-macrophage interaction. NHWD-870 increases tumor apoptosis and inhibits tumor proliferation.
Molecular Formula C29H29N7O
Molecular Weight 491.59