2115742-03-3
2115742-03-3 structure
- Name: NHWD-870
- Chemical Name: NHWD-870
- CAS Number: 2115742-03-3
- Molecular Formula: C29H29N7O
- Molecular Weight: 491.59
- Create Date: 2021-09-11 19:59:32
- Modify Date: 2025-08-24 04:22:08
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NHWD-870 is a potent, orally active and selective BET family bromodomain and only binds bromodomains of BRD2, BRD3, BRD4 (IC50=2.7 nM), and BRDT. NHWD-870 has potent tumor suppressive efficacies and suppresses cancer cell-macrophage interaction. NHWD-870 increases tumor apoptosis and inhibits tumor proliferation.
| Name | NHWD-870 |
|---|
| Description | NHWD-870 is a potent, orally active and selective BET family bromodomain and only binds bromodomains of BRD2, BRD3, BRD4 (IC50=2.7 nM), and BRDT. NHWD-870 has potent tumor suppressive efficacies and suppresses cancer cell-macrophage interaction. NHWD-870 increases tumor apoptosis and inhibits tumor proliferation. |
|---|
| Molecular Formula | C29H29N7O |
|---|---|
| Molecular Weight | 491.59 |