NHWD-870

Modify Date: 2024-01-05 19:50:52

NHWD-870 Structure
NHWD-870 structure
Common Name NHWD-870
CAS Number 2115742-03-3 Molecular Weight 491.59
Density N/A Boiling Point N/A
Molecular Formula C29H29N7O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of NHWD-870


NHWD-870 is a potent, orally active and selective BET family bromodomain and only binds bromodomains of BRD2, BRD3, BRD4 (IC50=2.7 nM), and BRDT. NHWD-870 has potent tumor suppressive efficacies and suppresses cancer cell-macrophage interaction. NHWD-870 increases tumor apoptosis and inhibits tumor proliferation.

 Names

Name NHWD-870

 NHWD-870 Biological Activity

Description NHWD-870 is a potent, orally active and selective BET family bromodomain and only binds bromodomains of BRD2, BRD3, BRD4 (IC50=2.7 nM), and BRDT. NHWD-870 has potent tumor suppressive efficacies and suppresses cancer cell-macrophage interaction. NHWD-870 increases tumor apoptosis and inhibits tumor proliferation.

 Chemical & Physical Properties

Molecular Formula C29H29N7O
Molecular Weight 491.59
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