2074702-04-6
2074702-04-6 structure
- Name: TNF-α-IN-2
- Chemical Name: TNF-α-IN-2
- CAS Number: 2074702-04-6
- Molecular Formula: C25H21ClF2N6O
- Molecular Weight: 494.92
- Create Date: 2021-09-13 17:25:09
- Modify Date: 2025-08-25 14:04:25
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TNF-α-IN-2 is a potent and orally active of tumor necrosis factor alpha (TNFα), with an IC50 of 25 nM in the HTRF assay. TNF-α-IN-2 distorts the TNFα trimer upon binding, leading to aberrant signaling when the trimer binds to TNFR1. TNF-α-IN-2 can be used for the research of rheumatoid arthritis.
| Name | TNF-α-IN-2 |
|---|
| Description | TNF-α-IN-2 is a potent and orally active of tumor necrosis factor alpha (TNFα), with an IC50 of 25 nM in the HTRF assay. TNF-α-IN-2 distorts the TNFα trimer upon binding, leading to aberrant signaling when the trimer binds to TNFR1. TNF-α-IN-2 can be used for the research of rheumatoid arthritis. |
|---|
| Molecular Formula | C25H21ClF2N6O |
|---|---|
| Molecular Weight | 494.92 |