342595-74-8
342595-74-8 structure
- Name: UMK57
- Chemical Name: 5-(4-Methylphenyl)-4-(1-pyrrolidinyl)thieno[2,3-d]pyrimidine
- CAS Number: 342595-74-8
- Molecular Formula: C17H17N3S
- Molecular Weight: 295.40
- Catalog: Research Areas Others
- Create Date: 2021-05-29 13:29:26
- Modify Date: 2025-08-25 05:59:11
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UMK57 is a small molecule compound that specifically promotes k-MT attachment error correction to inhibit chromosome missegregation, which can improve chromosome segregation fidelity by destabilizing kinetochore microtubule (k-MT) attachment during mitosis[1].
| Name | 5-(4-Methylphenyl)-4-(1-pyrrolidinyl)thieno[2,3-d]pyrimidine |
|---|---|
| Synonyms |
5-(4-Methylphenyl)-4-(1-pyrrolidinyl)thieno[2,3-d]pyrimidine
5-(4-Methylphenyl)-4-(pyrrolidin-1-yl)thieno[2,3-d]pyrimidine |
| Description | UMK57 is a small molecule compound that specifically promotes k-MT attachment error correction to inhibit chromosome missegregation, which can improve chromosome segregation fidelity by destabilizing kinetochore microtubule (k-MT) attachment during mitosis[1]. |
|---|---|
| Related Catalog | |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 492.5±45.0 °C at 760 mmHg |
| Molecular Formula | C17H17N3S |
| Molecular Weight | 295.40 |
| Flash Point | 251.7±28.7 °C |
| Exact Mass | 295.114319 |
| LogP | 4.12 |
| Vapour Pressure | 0.0±1.2 mmHg at 25°C |
| Index of Refraction | 1.673 |