2457232-14-1
2457232-14-1 structure
- Name: G6PDi-1
- Chemical Name: G6PDi-1
- CAS Number: 2457232-14-1
- Molecular Formula: C14H12N4OS
- Molecular Weight: 284.34
- Catalog: Research Areas Inflammation/Immunology
- Create Date: 2021-08-17 15:14:28
- Modify Date: 2025-08-25 15:40:19
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G6PDi-1 is a reversible and non-competitive glucose-6-phosphate dehydrogenase (G6PD) inhibitor with an IC50 of 0.07 μM. G6PDi-1 depletes NADPH most strongly in lymphocytes. G6PDi-1 markedly decreases inflammatory cytokine production in T cells[1].
| Name | G6PDi-1 |
|---|---|
| Synonyms |
4-[(5-Oxo-6,7,8,9-tetrahydro-5H-cyclohepta[d]pyrimidin-2-yl)amino]-2-thiophenecarbonitrile
G6PDi-1 2-Thiophenecarbonitrile, 4-[(6,7,8,9-tetrahydro-5-oxo-5H-cyclohepta[d]pyrimidin-2-yl)amino]- |
| Description | G6PDi-1 is a reversible and non-competitive glucose-6-phosphate dehydrogenase (G6PD) inhibitor with an IC50 of 0.07 μM. G6PDi-1 depletes NADPH most strongly in lymphocytes. G6PDi-1 markedly decreases inflammatory cytokine production in T cells[1]. |
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| Related Catalog | |
| References |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 527.6±60.0 °C at 760 mmHg |
| Molecular Formula | C14H12N4OS |
| Molecular Weight | 284.34 |
| Flash Point | 272.9±32.9 °C |
| Exact Mass | 284.073181 |
| LogP | 2.51 |
| Vapour Pressure | 0.0±1.4 mmHg at 25°C |
| Index of Refraction | 1.658 |
| Hazard Codes | Xi |
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