1452396-11-0

1452396-11-0 structure

Name: Sartorypyrone B
Chemical Name: Sartorypyrone B
CAS Number: 1452396-11-0
Molecular Formula: C₃₀H₄₂O₇
Molecular Weight: 514.650
Catalog: Research Areas Cancer
Create Date: 2021-05-23 21:14:52
Modify Date: 2025-08-25 19:33:10
Sartorypyrone B is a 2β-acetoxyl analogue of chevalone C. Sartorypyrone B is yielded from the ethyl acetate extract of the culture of the marine sponge-associated fungus Neosartorya tsunodae (KUFC 9213). Sartorypyrone B exhibits strong growth inhibitory activity, having GI50s of 17.8, 20.5, and 25.0 μM, respectively, for MCF-7, NCI-H460, and A375-C5. Sartorypyrone B has the potential for the research of breast adenocarcinoma, non-small cell lung cancer, and melanoma diseases[1].

Name	Sartorypyrone B
Synonyms	sartorypyrone B 1H,11H-Phenanthro[2,1-b]pyrano[3,2-e]pyran-11-one, 2,3-bis(acetyloxy)-2,3,4,4a,4b,5,6,6a,12,12a,12b,13,14,14a-tetradecahydro-1,1,4a,6a,9,12b-hexamethyl-, (2R,3S,4aR,4bR,6aS,12aS,12bR,14aR)- (2R,3S,4aR,4bR,6aS,12aS,12bR,14aR)-1,1,4a,6a,9,12b-Hexamethyl-11-oxo-2,3,4,4a,4b,5,6,6a,12,12a,12b,13,14,14a-tetradecahydro-1H,11H-naphtho[2,1-f]pyrano[2,3-b]chromene-2,3-diyl diacetate

Description	Sartorypyrone B is a 2β-acetoxyl analogue of chevalone C. Sartorypyrone B is yielded from the ethyl acetate extract of the culture of the marine sponge-associated fungus Neosartorya tsunodae (KUFC 9213). Sartorypyrone B exhibits strong growth inhibitory activity, having GI50s of 17.8, 20.5, and 25.0 μM, respectively, for MCF-7, NCI-H460, and A375-C5. Sartorypyrone B has the potential for the research of breast adenocarcinoma, non-small cell lung cancer, and melanoma diseases[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
References	[1]. Amnat Eamvijarn, et al. Bioactive meroditerpenes and indole alkaloids from the soil fungus Neosartorya fischeri (KUFC 6344), and the marine-derived fungi Neosartorya laciniosa (KUFC 7896) and Neosartorya tsunodae (KUFC 9213).