Sartorypyrone B

Modify Date: 2024-01-29 22:52:48

Sartorypyrone B Structure
Sartorypyrone B structure
Common Name Sartorypyrone B
CAS Number 1452396-11-0 Molecular Weight 514.650
Density 1.2±0.1 g/cm3 Boiling Point 582.6±50.0 °C at 760 mmHg
Molecular Formula C30H42O7 Melting Point N/A
MSDS N/A Flash Point 244.0±30.2 °C

 Use of Sartorypyrone B


Sartorypyrone B is a 2β-acetoxyl analogue of chevalone C. Sartorypyrone B is yielded from the ethyl acetate extract of the culture of the marine sponge-associated fungus Neosartorya tsunodae (KUFC 9213). Sartorypyrone B exhibits strong growth inhibitory activity, having GI50s of 17.8, 20.5, and 25.0 μM, respectively, for MCF-7, NCI-H460, and A375-C5. Sartorypyrone B has the potential for the research of breast adenocarcinoma, non-small cell lung cancer, and melanoma diseases[1].

 Names

Name Sartorypyrone B
Synonym More Synonyms

 Sartorypyrone B Biological Activity

Description Sartorypyrone B is a 2β-acetoxyl analogue of chevalone C. Sartorypyrone B is yielded from the ethyl acetate extract of the culture of the marine sponge-associated fungus Neosartorya tsunodae (KUFC 9213). Sartorypyrone B exhibits strong growth inhibitory activity, having GI50s of 17.8, 20.5, and 25.0 μM, respectively, for MCF-7, NCI-H460, and A375-C5. Sartorypyrone B has the potential for the research of breast adenocarcinoma, non-small cell lung cancer, and melanoma diseases[1].
Related Catalog
References

[1]. Amnat Eamvijarn, et al. Bioactive meroditerpenes and indole alkaloids from the soil fungus Neosartorya fischeri (KUFC 6344), and the marine-derived fungi Neosartorya laciniosa (KUFC 7896) and Neosartorya tsunodae (KUFC 9213).

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 582.6±50.0 °C at 760 mmHg
Molecular Formula C30H42O7
Molecular Weight 514.650
Flash Point 244.0±30.2 °C
Exact Mass 514.293030
LogP 5.84
Vapour Pressure 0.0±1.6 mmHg at 25°C
Index of Refraction 1.550

 Synonyms

sartorypyrone B
1H,11H-Phenanthro[2,1-b]pyrano[3,2-e]pyran-11-one, 2,3-bis(acetyloxy)-2,3,4,4a,4b,5,6,6a,12,12a,12b,13,14,14a-tetradecahydro-1,1,4a,6a,9,12b-hexamethyl-, (2R,3S,4aR,4bR,6aS,12aS,12bR,14aR)-
(2R,3S,4aR,4bR,6aS,12aS,12bR,14aR)-1,1,4a,6a,9,12b-Hexamethyl-11-oxo-2,3,4,4a,4b,5,6,6a,12,12a,12b,13,14,14a-tetradecahydro-1H,11H-naphtho[2,1-f]pyrano[2,3-b]chromene-2,3-diyl diacetate
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