1200128-66-0
1200128-66-0 structure
- Name: 18-Deoxyherboxidiene
- Chemical Name: 18-Deoxyherboxidiene
- CAS Number: 1200128-66-0
- Molecular Formula: C25H42O5
- Molecular Weight: 422.598
- Catalog: Research Areas Cancer
- Create Date: 2021-06-02 07:30:54
- Modify Date: 2025-08-25 12:07:18
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18-Deoxyherboxidiene (RQN-18690A) is a potent angiogenesis inhibitor. 18-Deoxyherboxidiene targets SF3b, a spliceosome component that is a subcomplex of the U2 small nuclear ribonucleoprotein (snRNP) in the spliceosome. 18-Deoxyherboxidiene inhibits the migration and tube formation of human umbilical vein endothelial cells (HUVECs) without significant cell toxicity. 18-Deoxyherboxidiene has the potential for cancer research[1].
| Name | 18-Deoxyherboxidiene |
|---|---|
| Synonyms |
{(2R,5S,6S)-6-[(2E,4E,6S)-7-{(2R,3R)-3-[(2R,3S)-3-Methoxy-2-pentanyl]-2-methyl-2-oxiranyl}-6-methyl-2,4-heptadien-2-yl]-5-methyltetrahydro-2H-pyran-2-yl}acetic acid
2H-Pyran-2-acetic acid, tetrahydro-6-[(1E,3E,5S)-6-[(2R,3R)-3-[(1R,2S)-2-methoxy-1-methylbutyl]-2-methyloxiranyl]-1,5-dimethyl-1,3-hexadien-1-yl]-5-methyl-, (2R,5S,6S)- 18-Deoxyherboxidiene |
| Description | 18-Deoxyherboxidiene (RQN-18690A) is a potent angiogenesis inhibitor. 18-Deoxyherboxidiene targets SF3b, a spliceosome component that is a subcomplex of the U2 small nuclear ribonucleoprotein (snRNP) in the spliceosome. 18-Deoxyherboxidiene inhibits the migration and tube formation of human umbilical vein endothelial cells (HUVECs) without significant cell toxicity. 18-Deoxyherboxidiene has the potential for cancer research[1]. |
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| Related Catalog | |
| References |
| Density | 1.0±0.1 g/cm3 |
|---|---|
| Boiling Point | 525.2±30.0 °C at 760 mmHg |
| Molecular Formula | C25H42O5 |
| Molecular Weight | 422.598 |
| Flash Point | 165.7±18.1 °C |
| Exact Mass | 422.303223 |
| LogP | 4.21 |
| Vapour Pressure | 0.0±3.0 mmHg at 25°C |
| Index of Refraction | 1.487 |