62354-65-8

62354-65-8 structure

Name: H-D-Phe-Pip-Arg-pNA dihydrochloride
Chemical Name: H-D-Phe-Pip-Arg-pNA dihydrochloride
CAS Number: 62354-65-8
Molecular Formula: C₂₇H₃₈Cl₂N₈O₅
Molecular Weight: 625.55
Catalog: Research Areas Others
Create Date: 2021-01-13 21:35:00
Modify Date: 2024-01-04 21:40:29
H-D-Phe-Pip-Arg-pNA (S-2238) dihydrochloride, a chromogenic substrate, is patterned after the N-terminal portion of the A alpha chain of fibrinogen, which is the natural substrate of thrombin. H-D-Phe-Pip-Arg-pNA dihydrochloride is specific for thrombin and is used to measure antithrombin-heparin cofactor (AT-III). The AT-III assay using H-D-Phe-Pip-Arg-pNA dihydrochloride is sensitive, accurate, and easy to perform[1][2].

Name	H-D-Phe-Pip-Arg-pNA dihydrochloride

Description	H-D-Phe-Pip-Arg-pNA (S-2238) dihydrochloride, a chromogenic substrate, is patterned after the N-terminal portion of the A alpha chain of fibrinogen, which is the natural substrate of thrombin. H-D-Phe-Pip-Arg-pNA dihydrochloride is specific for thrombin and is used to measure antithrombin-heparin cofactor (AT-III). The AT-III assay using H-D-Phe-Pip-Arg-pNA dihydrochloride is sensitive, accurate, and easy to perform[1][2].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. Goodnight SH Jr, et al. Measurement of antithrombin III in normal and pathologic states using chromogenic substrate S-2238. Comparison with immunoelectrophoretic and factor Xa inhibition assays. Am J Clin Pathol. 1980;73(5):639-647. [2]. Voorthuizen H, Kluft C. Improved assay conditions for automated antithrombin III determinations with the chromogenic substrate S-2238. Thromb Haemost. 1984;52(3):350-353.

Molecular Formula	C₂₇H₃₈Cl₂N₈O₅
Molecular Weight	625.55