2374703-19-0
2374703-19-0 structure
- Name: MR-L2
- Chemical Name: MR-L2
- CAS Number: 2374703-19-0
- Molecular Formula: C19H16Cl3FN4O
- Molecular Weight: 441.71
- Create Date: 2021-01-10 16:13:40
- Modify Date: 2024-04-08 21:17:41
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MR-L2 is a reversible and noncompetitive allosteric activator of long-isoform phosphodiesterase-4 (PDE4), activates representative PDE4 long-isoform variants (PDE4A4, PDE4B1, PDE4C3, PDE4D5). MR-L2 suppresses PGE2-induced MDCK cell cyst formation with an EC50 of 1.2 μM.
| Name | MR-L2 |
|---|
| Description | MR-L2 is a reversible and noncompetitive allosteric activator of long-isoform phosphodiesterase-4 (PDE4), activates representative PDE4 long-isoform variants (PDE4A4, PDE4B1, PDE4C3, PDE4D5). MR-L2 suppresses PGE2-induced MDCK cell cyst formation with an EC50 of 1.2 μM. |
|---|
| Molecular Formula | C19H16Cl3FN4O |
|---|---|
| Molecular Weight | 441.71 |
| Storage condition | -20°C |