MR-L2
Modify Date: 2025-11-25 16:04:49
MR-L2 structure
|
Common Name | MR-L2 | ||
|---|---|---|---|---|
| CAS Number | 2374703-19-0 | Molecular Weight | 441.71 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C19H16Cl3FN4O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of MR-L2MR-L2 is a reversible and noncompetitive allosteric activator of long-isoform phosphodiesterase-4 (PDE4), activates representative PDE4 long-isoform variants (PDE4A4, PDE4B1, PDE4C3, PDE4D5). MR-L2 suppresses PGE2-induced MDCK cell cyst formation with an EC50 of 1.2 μM. |
| Name | MR-L2 |
|---|
| Description | MR-L2 is a reversible and noncompetitive allosteric activator of long-isoform phosphodiesterase-4 (PDE4), activates representative PDE4 long-isoform variants (PDE4A4, PDE4B1, PDE4C3, PDE4D5). MR-L2 suppresses PGE2-induced MDCK cell cyst formation with an EC50 of 1.2 μM. |
|---|
| Molecular Formula | C19H16Cl3FN4O |
|---|---|
| Molecular Weight | 441.71 |
| InChIKey | JXACCOKEEPXHCF-UHFFFAOYSA-N |
| SMILES | CCc1nc(-c2ccc(Cl)c(F)c2)nn1CC(=O)NCc1cc(Cl)cc(Cl)c1 |
| Storage condition | -20°C |