1301757-19-6
1301757-19-6 structure
- Name: MC2050 HCl
- Chemical Name: MC2050 HCl
- CAS Number: 1301757-19-6
- Molecular Formula: C19H23Cl2N5Os
- Molecular Weight: 440.387
- Create Date: 2021-01-08 19:07:32
- Modify Date: 2025-09-18 23:32:18
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MC2050 is a potent PARP-1 inhibitor. The IC50 for inhibition of PARP-1 activity is 119 nM, compared to 1.8 μM for PARP-2. MC2050 inhibits apoptosis and blocks poly ADP-ribosylation of histone H1 in hydrogen peroxide treated SH-SY5Y neuroblastoma cells.
| Name | MC2050 HCl |
|---|
| Description | MC2050 is a potent PARP-1 inhibitor. The IC50 for inhibition of PARP-1 activity is 119 nM, compared to 1.8 μM for PARP-2. MC2050 inhibits apoptosis and blocks poly ADP-ribosylation of histone H1 in hydrogen peroxide treated SH-SY5Y neuroblastoma cells. |
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| Molecular Formula | C19H23Cl2N5Os |
|---|---|
| Molecular Weight | 440.387 |