1284150-65-7
1284150-65-7 structure
- Name: Azeliragon HCl
- Chemical Name: 3-(4-{2-Butyl-1-[4-(4-chlorophenoxy)phenyl]-1H-imidazol-4-yl}phenoxy)-N,N-diethyl-1-propanamine dihydrochloride
- CAS Number: 1284150-65-7
- Molecular Formula: C32H40Cl3N3O2
- Molecular Weight: 605.038
- Create Date: 2021-01-08 18:03:38
- Modify Date: 2024-01-19 13:57:00
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Azeliragon, also known as TTP488 and PF-04494700, is a potent and orally active RAGE inhibitor. RAGE (receptor for advanced glycation endproducts) is a pattern recognition receptor, which affects the movement of amyloid, an Alzheimer's-associated protein, into the brain. In preclinical studies, azeliragon decreased brain amyloid in mice and improved their performance on behavior tests. Azeliragon is a promising agent for for Alzheimer's disease and cerebral amyloid angiopathy.
| Name | 3-(4-{2-Butyl-1-[4-(4-chlorophenoxy)phenyl]-1H-imidazol-4-yl}phenoxy)-N,N-diethyl-1-propanamine dihydrochloride |
|---|---|
| Synonyms |
1-Propanamine, 3-[4-[2-butyl-1-[4-(4-chlorophenoxy)phenyl]-1H-imidazol-4-yl]phenoxy]-N,N-diethyl-, hydrochloride (1:2)
3-(4-{2-Butyl-1-[4-(4-chlorophenoxy)phenyl]-1H-imidazol-4-yl}phenoxy)-N,N-diethyl-1-propanamine dihydrochloride |
| Molecular Formula | C32H40Cl3N3O2 |
|---|---|
| Molecular Weight | 605.038 |
| Exact Mass | 603.218628 |