2129164-91-4

2129164-91-4 structure

Name: DBCO-PEG4-VC-PAB-MMAE
Chemical Name: DBCO-PEG4-VC-PAB-MMAE
CAS Number: 2129164-91-4
Molecular Formula: C₈₈H₁₂₈N₁₂O₁₉
Molecular Weight: 1658.03
Create Date: 2020-08-10 20:08:10
Modify Date: 2024-01-24 23:00:59
DBCO-PEG4-VC-PAB-MMAE consists a ADC linker (DBCO-PEG4-VC-PAB) and a tubulin polymerization inhibitor MMAE (HY-15162). DBCO-PEG4-VC-PAB-MMAE can be used in the synthesis of antibody-drug conjugates (ADCs). MMAE is a synthetic derivative of dolastatin 10 and functions as a potent mitotic inhibitor by inhibiting tubulin polymerization[1].

Name	DBCO-PEG4-VC-PAB-MMAE

Description	DBCO-PEG4-VC-PAB-MMAE consists a ADC linker (DBCO-PEG4-VC-PAB) and a tubulin polymerization inhibitor MMAE (HY-15162). DBCO-PEG4-VC-PAB-MMAE can be used in the synthesis of antibody-drug conjugates (ADCs). MMAE is a synthetic derivative of dolastatin 10 and functions as a potent mitotic inhibitor by inhibiting tubulin polymerization[1].
Related Catalog	Research Areas >> Cancer
Target	Duocarmycins
References	[1]. Okeley, et al. Intracellular Activation of SGN-35, a Potent Anti-CD30 Antibody-Drug Conjugate. Clinical Cancer Research (2010), 16(3), 888-897.

Molecular Formula	C₈₈H₁₂₈N₁₂O₁₉
Molecular Weight	1658.03

Hazard Codes	Xi