151804-79-4
151804-79-4 structure
- Name: AC 253
- Chemical Name: AC 253
- CAS Number: 151804-79-4
- Molecular Formula: C122H196N40O39
- Molecular Weight: 2847.11
- Create Date: 2020-08-10 19:23:54
- Modify Date: 2024-04-06 11:44:56
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AC 253 is an Amylin (AMY3) receptor antagonist, inhibiting andrenomedulin-stimulated cAMP production. AC 253 protects against oligomeric Aβ-induced increase in intracellular Ca2+, activation of PKA, MAPK, Akt and cFOS and cell death in neuronal cell culture. AC 253 blocks electrophysiological effects of Aβ.
| Name | AC 253 |
|---|
| Description | AC 253 is an Amylin (AMY3) receptor antagonist, inhibiting andrenomedulin-stimulated cAMP production. AC 253 protects against oligomeric Aβ-induced increase in intracellular Ca2+, activation of PKA, MAPK, Akt and cFOS and cell death in neuronal cell culture. AC 253 blocks electrophysiological effects of Aβ. |
|---|
| Molecular Formula | C122H196N40O39 |
|---|---|
| Molecular Weight | 2847.11 |
| Storage condition | -20°C |