AC 253
Modify Date: 2025-08-29 07:17:28
AC 253 structure
|
Common Name | AC 253 | ||
|---|---|---|---|---|
| CAS Number | 151804-79-4 | Molecular Weight | 2847.11 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C122H196N40O39 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of AC 253AC 253 is an Amylin (AMY3) receptor antagonist, inhibiting andrenomedulin-stimulated cAMP production. AC 253 protects against oligomeric Aβ-induced increase in intracellular Ca2+, activation of PKA, MAPK, Akt and cFOS and cell death in neuronal cell culture. AC 253 blocks electrophysiological effects of Aβ. |
| Name | AC 253 |
|---|
| Description | AC 253 is an Amylin (AMY3) receptor antagonist, inhibiting andrenomedulin-stimulated cAMP production. AC 253 protects against oligomeric Aβ-induced increase in intracellular Ca2+, activation of PKA, MAPK, Akt and cFOS and cell death in neuronal cell culture. AC 253 blocks electrophysiological effects of Aβ. |
|---|
| Molecular Formula | C122H196N40O39 |
|---|---|
| Molecular Weight | 2847.11 |
| InChIKey | QOVDFCPGVUGNIP-MLZIZKOLSA-N |
| SMILES | CC(=O)NC(CC(C)C)C(=O)NCC(=O)NC(CCCNC(=N)N)C(=O)NC(CC(C)C)C(=O)NC(CO)C(=O)NC(CCC(N)=O)C(=O)NC(CCC(=O)O)C(=O)NC(CC(C)C)C(=O)NC(Cc1c[nH]cn1)C(=O)NC(CCCNC(=N)N)C(=O)NC(CC(C)C)C(=O)NC(CCC(N)=O)C(=O)NC(C(=O)NC(Cc1ccc(O)cc1)C(=O)N1CCCC1C(=O)NC(CCCNC(=N)N)C(=O)NC(C(=O)NC(CC(N)=O)C(=O)NC(C(=O)NCC(=O)NC(CO)C(=O)NC(CC(N)=O)C(=O)NC(C(=O)NC(Cc1ccc(O)cc1)C(N)=O)C(C)O)C(C)O)C(C)O)C(C)O |
| Storage condition | -20°C |