AC 253

Modify Date: 2024-04-06 11:44:56

AC 253 Structure
AC 253 structure
Common Name AC 253
CAS Number 151804-79-4 Molecular Weight 2847.11
Density N/A Boiling Point N/A
Molecular Formula C122H196N40O39 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of AC 253


AC 253 is an Amylin (AMY3) receptor antagonist, inhibiting andrenomedulin-stimulated cAMP production. AC 253 protects against oligomeric Aβ-induced increase in intracellular Ca2+, activation of PKA, MAPK, Akt and cFOS and cell death in neuronal cell culture. AC 253 blocks electrophysiological effects of Aβ.

 Names

Name AC 253

 AC 253 Biological Activity

Description AC 253 is an Amylin (AMY3) receptor antagonist, inhibiting andrenomedulin-stimulated cAMP production. AC 253 protects against oligomeric Aβ-induced increase in intracellular Ca2+, activation of PKA, MAPK, Akt and cFOS and cell death in neuronal cell culture. AC 253 blocks electrophysiological effects of Aβ.

 Chemical & Physical Properties

Molecular Formula C122H196N40O39
Molecular Weight 2847.11
Storage condition -20°C