2410327-94-3

2410327-94-3 structure

Name: 6'-GNTI dihydrochloride
Chemical Name: 6'-GNTI dihydrochloride
CAS Number: 2410327-94-3
Molecular Formula: C₂₇H₃₁Cl₂N₅O₃
Molecular Weight: 544.47
Catalog: Signaling Pathways GPCR/G Protein Opioid Receptor
Create Date: 2020-08-10 23:04:29
Modify Date: 2024-01-10 17:56:21
6'-GNTI dihydrochloride, a κ-opioid receptor (KOR) agonist, displays bias toward the activation of G protein-mediated signaling over β-arrestin2 recruitment. 6'-GNTI 6'-GNTI dihydrochloride only activates the Akt pathway in striatal neurons[1].

Name	6'-GNTI dihydrochloride

Description	6'-GNTI dihydrochloride, a κ-opioid receptor (KOR) agonist, displays bias toward the activation of G protein-mediated signaling over β-arrestin2 recruitment. 6'-GNTI 6'-GNTI dihydrochloride only activates the Akt pathway in striatal neurons[1].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Opioid Receptor Signaling Pathways >> Neuronal Signaling >> Opioid Receptor Research Areas >> Neurological Disease
References	[1]. Schmid CL, et al. Functional selectivity of 6'-guanidinonaltrindole (6'-GNTI) at κ-opioid receptors in striatal neurons. J Biol Chem. 2013;288(31):22387-22398.

Molecular Formula	C₂₇H₃₁Cl₂N₅O₃
Molecular Weight	544.47