2089227-65-4

2089227-65-4 structure
2089227-65-4 structure
  • Name: VBIT-12
  • Chemical Name: VBIT-12
  • CAS Number: 2089227-65-4
  • Molecular Formula: C25H27N3O3
  • Molecular Weight: 417.50
  • Catalog: Research Areas Neurological Disease
  • Create Date: 2020-06-01 21:08:09
  • Modify Date: 2025-08-25 10:20:48
  • VBIT-12 is a potent VDAC1 inhibitor. VBIT-12 directly interacts with VDAC1 and prevents VDAC1 oligomerization, and thus inhibits apoptotic action of VDAC1[1].

Name VBIT-12
Description VBIT-12 is a potent VDAC1 inhibitor. VBIT-12 directly interacts with VDAC1 and prevents VDAC1 oligomerization, and thus inhibits apoptotic action of VDAC1[1].
Related Catalog
Target

VDAC1[1]

In Vitro VBIT-12 inhibits VDAC1 oligomerization, hexokinase (HK) detachment and apoptotic cell death[1].
References

[1]. Shoshan-Barmatz V, et al. VDAC1, mitochondrial dysfunction, and Alzheimer's disease. Pharmacol Res. 2018 May;131:87-101.

Molecular Formula C25H27N3O3
Molecular Weight 417.50
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