552332-71-5
552332-71-5 structure
- Name: Db07107
- Chemical Name: DB07107
- CAS Number: 552332-71-5
- Molecular Formula: C23H22N4O
- Molecular Weight: 370.45
- Catalog: Signaling Pathways PI3K/Akt/mTOR Akt
- Create Date: 2020-06-01 14:31:22
- Modify Date: 2025-08-26 08:39:41
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DB07107 is a potent drug resistant T315I mutant Bcr-Abl tyrosine kinase inhibitor. DB07107 is also a potent Akt1 inhibitor with an IC50 value of 360 nM[1][2].
| Name | DB07107 |
|---|
| Description | DB07107 is a potent drug resistant T315I mutant Bcr-Abl tyrosine kinase inhibitor. DB07107 is also a potent Akt1 inhibitor with an IC50 value of 360 nM[1][2]. |
|---|---|
| Related Catalog | |
| Target |
Bcr-AblT315I Akt1:360 nM (IC50) |
| In Vitro | DB07107 is more effective in blocking drug-resistant T315I mutant than the wild-type Bcr-Abl. DB07107 (C23H22N4O) from DrugBank showed the highest binding energy with XP score of -14.045 kcal/mol[1]. |
| References |
| Molecular Formula | C23H22N4O |
|---|---|
| Molecular Weight | 370.45 |
| Hazard Codes | Xi |
|---|