1402057-88-8
1402057-88-8 structure
- Name: Cdc7-IN-6
- Chemical Name: Cdc7-IN-6
- CAS Number: 1402057-88-8
- Molecular Formula: C21H22F3N5O4
- Molecular Weight: 465.43
- Catalog: Signaling Pathways Cell Cycle/DNA Damage CDK
- Create Date: 2020-01-23 23:47:51
- Modify Date: 2025-09-12 04:40:39
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Cdc7-IN-6 (compound I-D) is a potent Cdc7 kinase inhibitor (IC50=4 nM), extracted from patent WO2019165473A1, compound I- D, has anti-tumor activity[1].
| Name | Cdc7-IN-6 |
|---|
| Description | Cdc7-IN-6 (compound I-D) is a potent Cdc7 kinase inhibitor (IC50=4 nM), extracted from patent WO2019165473A1, compound I- D, has anti-tumor activity[1]. |
|---|---|
| Related Catalog | |
| In Vitro | Cdc7-IN-6 demonstrates potent inhibitory activity (IC50<3 µΜ) in a range of solid tumor cell lines, including those of bladder (5673, RT1 12/84), sarcoma (143B, CADO-ES1, RD-ES, A673), colon and cecum (Colo-205, DLD-l, LS1034, SK-CO-l, SNU-C1), renal (U0.31), head-and-neck (CNE-2Z, RPMI-2650), melanoma (A2058, A875), and gastric (HGC-27) lineages[1]. |
| References |
| Molecular Formula | C21H22F3N5O4 |
|---|---|
| Molecular Weight | 465.43 |