Cdc7-IN-6

Modify Date: 2025-09-12 04:40:39

Cdc7-IN-6 Structure
Cdc7-IN-6 structure
Common Name Cdc7-IN-6
CAS Number 1402057-88-8 Molecular Weight 465.43
Density N/A Boiling Point N/A
Molecular Formula C21H22F3N5O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Cdc7-IN-6


Cdc7-IN-6 (compound I-D) is a potent Cdc7 kinase inhibitor (IC50=4 nM), extracted from patent WO2019165473A1, compound I- D, has anti-tumor activity[1].

 Names

Name Cdc7-IN-6

 Cdc7-IN-6 Biological Activity

Description Cdc7-IN-6 (compound I-D) is a potent Cdc7 kinase inhibitor (IC50=4 nM), extracted from patent WO2019165473A1, compound I- D, has anti-tumor activity[1].
Related Catalog
In Vitro Cdc7-IN-6 demonstrates potent inhibitory activity (IC50<3 µΜ) in a range of solid tumor cell lines, including those of bladder (5673, RT1 12/84), sarcoma (143B, CADO-ES1, RD-ES, A673), colon and cecum (Colo-205, DLD-l, LS1034, SK-CO-l, SNU-C1), renal (U0.31), head-and-neck (CNE-2Z, RPMI-2650), melanoma (A2058, A875), and gastric (HGC-27) lineages[1].
References

[1]. Christian Andrew HASSIG, et al. Methods of treatment of cancer comprising cdc7 inhibitors. WO2019165473A1.

 Chemical & Physical Properties

Molecular Formula C21H22F3N5O4
Molecular Weight 465.43
InChIKey HFBNZZVVRMLDJO-JLHYYAGUSA-N
SMILES CCOC(=O)c1c(NN2CCN(CC(F)(F)F)CC2)oc(C=C2C=Nc3ncccc32)c1O
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