Cdc7-IN-6 structure
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Common Name | Cdc7-IN-6 | ||
|---|---|---|---|---|
| CAS Number | 1402057-88-8 | Molecular Weight | 465.43 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C21H22F3N5O4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Cdc7-IN-6Cdc7-IN-6 (compound I-D) is a potent Cdc7 kinase inhibitor (IC50=4 nM), extracted from patent WO2019165473A1, compound I- D, has anti-tumor activity[1]. |
| Name | Cdc7-IN-6 |
|---|
| Description | Cdc7-IN-6 (compound I-D) is a potent Cdc7 kinase inhibitor (IC50=4 nM), extracted from patent WO2019165473A1, compound I- D, has anti-tumor activity[1]. |
|---|---|
| Related Catalog | |
| In Vitro | Cdc7-IN-6 demonstrates potent inhibitory activity (IC50<3 µΜ) in a range of solid tumor cell lines, including those of bladder (5673, RT1 12/84), sarcoma (143B, CADO-ES1, RD-ES, A673), colon and cecum (Colo-205, DLD-l, LS1034, SK-CO-l, SNU-C1), renal (U0.31), head-and-neck (CNE-2Z, RPMI-2650), melanoma (A2058, A875), and gastric (HGC-27) lineages[1]. |
| References |
| Molecular Formula | C21H22F3N5O4 |
|---|---|
| Molecular Weight | 465.43 |
| InChIKey | HFBNZZVVRMLDJO-JLHYYAGUSA-N |
| SMILES | CCOC(=O)c1c(NN2CCN(CC(F)(F)F)CC2)oc(C=C2C=Nc3ncccc32)c1O |