DC Chemicals Limited
China
Product Name: (2S,3S)-E1R
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Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

1424832-57-4

1424832-57-4 structure

1424832-57-4 structure

Name: (2S,3S)-E1R
Chemical Name: (2S,3S)-E1R
CAS Number: 1424832-57-4
Molecular Formula: C₁₃H₁₆N₂O₂
Molecular Weight: 232.28
Catalog: Signaling Pathways GPCR/G Protein Sigma Receptor
Create Date: 2020-01-23 19:42:51
Modify Date: 2024-01-09 16:36:02
(2S,3S)-E1R (Compound 2d) is an enantiomer of E1R. (2S,3S)-E1R is a sigma-1 receptor positive allosteric modulator (Sig1R PAM) for the treatment of cognition/memory disorders[1].

Name	(2S,3S)-E1R

Description	(2S,3S)-E1R (Compound 2d) is an enantiomer of E1R. (2S,3S)-E1R is a sigma-1 receptor positive allosteric modulator (Sig1R PAM) for the treatment of cognition/memory disorders[1].
Related Catalog	Research Areas >> Neurological Disease Signaling Pathways >> GPCR/G Protein >> Sigma Receptor
In Vitro	Sigma-1 receptor plays an important role in neuronal plasticity, a process implicated in the pathophysiology of neuropsychiatric diseases, such as Alzheimer’s disease, major depressive disorders, and schizophrenia[1].
References	[1]. Veinberg G, et al. Synthesis and biological evaluation of 2-(5-methyl-4-phenyl-2-oxopyrrolidin-1-yl)-acetamide stereoisomers as novel positive allosteric modulators of sigma-1 receptor. Bioorg Med Chem. 2013 May 15;21(10):2764-71.

Molecular Formula	C₁₃H₁₆N₂O₂
Molecular Weight	232.28