878022-36-7
878022-36-7 structure
- Name: NU-8231
- Chemical Name: NU-8231
- CAS Number: 878022-36-7
- Molecular Formula: C26H26ClNO5
- Molecular Weight: 467.95
- Create Date: 2020-01-20 10:41:56
- Modify Date: 2025-08-25 10:55:22
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A small molecule inhibitor of MDM2-p53 protein-protein interaction with IC50 of 5.3 uM in ELISA assay; induces p53-dependent gene transcription SJSA human sarcoma cell line.
| Name | NU-8231 |
|---|
| Description | A small molecule inhibitor of MDM2-p53 protein-protein interaction with IC50 of 5.3 uM in ELISA assay; induces p53-dependent gene transcription SJSA human sarcoma cell line. |
|---|---|
| References | References 1. Hardcastle IR, et al. Bioorg Med Chem Lett. 2005 Mar 1;15(5):1515-20. 2. Hardcastle IR, et al. J Med Chem. 2011 Mar 10;54(5):1233-43. View Related Products by Target MDM2-p53 |
| Molecular Formula | C26H26ClNO5 |
|---|---|
| Molecular Weight | 467.95 |