1926204-95-6
1926204-95-6 structure
- Name: G-9791
- Chemical Name: G-9791
- CAS Number: 1926204-95-6
- Molecular Formula: C26H26ClFN6O2
- Molecular Weight: 508.98
- Create Date: 2020-01-11 15:28:50
- Modify Date: 2024-01-21 19:46:41
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A potent and selective group I PAK (pan-PAK1/2/3) inhibitor with Ki of 0.95/2 nM for PAK1/2, respectively; displays 57-fold selectivity over Lck kinase; inhibits the phosphorylation of residue S298 of MEK1 in EBC1 cells with IC50 of 33 nM.
| Name | G-9791 |
|---|
| Description | A potent and selective group I PAK (pan-PAK1/2/3) inhibitor with Ki of 0.95/2 nM for PAK1/2, respectively; displays 57-fold selectivity over Lck kinase; inhibits the phosphorylation of residue S298 of MEK1 in EBC1 cells with IC50 of 33 nM. |
|---|---|
| References | References 1. Rudolph J, et al. J Med Chem. 2016 Jun 9;59(11):5520-41. View Related Products by Target p21-activated Kinase (PAK) |
| Molecular Formula | C26H26ClFN6O2 |
|---|---|
| Molecular Weight | 508.98 |