1883372-87-9
1883372-87-9 structure
- Name: YIR-819 TFA salt
- Chemical Name: YIR-819 TFA salt
- CAS Number: 1883372-87-9
- Molecular Formula: C25H35ClF3N7O5
- Molecular Weight: 606.044
- Create Date: 2020-01-11 18:50:00
- Modify Date: 2024-04-11 22:42:25
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YIR-819 is a small-molecule CD4 mimic that acts as a highly potent HIV entry inhibitor with IC50 of 2.6 uM against YTA48P virus with no significant cytotoxicity (CC50=33 uM); A useful lead compound for the further development of HIV-1 entry inhibitors and could potentially be useful for co-administration with neutralizing antibodies for the treatment of HIV infection and AIDS.
| Name | YIR-819 TFA salt |
|---|
| Description | YIR-819 is a small-molecule CD4 mimic that acts as a highly potent HIV entry inhibitor with IC50 of 2.6 uM against YTA48P virus with no significant cytotoxicity (CC50=33 uM); A useful lead compound for the further development of HIV-1 entry inhibitors and could potentially be useful for co-administration with neutralizing antibodies for the treatment of HIV infection and AIDS. |
|---|---|
| References | References 1. Ohashi N, et al. ChemMedChem. 2016 Apr 19;11(8):940-6. 2. Boonstra A, et al. Antivir Ther. 2012;17(4):657-67. View Related Products by Target HIV |
| Molecular Formula | C25H35ClF3N7O5 |
|---|---|
| Molecular Weight | 606.044 |