1883372-86-8
1883372-86-8 structure
- Name: YIR-819
- Chemical Name: YIR-819
- CAS Number: 1883372-86-8
- Molecular Formula: C23H34ClN7O3
- Molecular Weight: 492.021
- Create Date: 2020-01-11 18:33:49
- Modify Date: 2025-10-28 15:24:53
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YIR-819 is a small-molecule CD4 mimic that acts as a highly potent HIV entry inhibitor with IC50 of 2.6 uM against YTA48P virus with no significant cytotoxicity (CC50=33 uM); A useful lead compound for the further development of HIV-1 entry inhibitors and could potentially be useful for co-administration with neutralizing antibodies for the treatment of HIV infection and AIDS.
| Name | YIR-819 |
|---|
| Description | YIR-819 is a small-molecule CD4 mimic that acts as a highly potent HIV entry inhibitor with IC50 of 2.6 uM against YTA48P virus with no significant cytotoxicity (CC50=33 uM); A useful lead compound for the further development of HIV-1 entry inhibitors and could potentially be useful for co-administration with neutralizing antibodies for the treatment of HIV infection and AIDS. |
|---|---|
| References | References 1. Ohashi N, et al. ChemMedChem. 2016 Apr 19;11(8):940-6. View Related Products by Target HIV |
| Molecular Formula | C23H34ClN7O3 |
|---|---|
| Molecular Weight | 492.021 |