1808115-35-6
1808115-35-6 structure
- Name: GPA 512
- Chemical Name: GPA 512
- CAS Number: 1808115-35-6
- Molecular Formula: C17H25NO6S
- Molecular Weight: 371.448
- Create Date: 2020-01-12 11:30:30
- Modify Date: 2024-09-18 14:42:32
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The orally bioavailable prodrug of Galiellalactone, a direct inhibitor of STAT3, prevents the transcription of STAT3 regulated genes; increases the plasma exposure of the active parent compound 20-fold compared to Galiellalactone; significantly reduces tumor growth in DU145 xenograft tumors.
| Name | GPA 512 |
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| Description | The orally bioavailable prodrug of Galiellalactone, a direct inhibitor of STAT3, prevents the transcription of STAT3 regulated genes; increases the plasma exposure of the active parent compound 20-fold compared to Galiellalactone; significantly reduces tumor growth in DU145 xenograft tumors. |
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| References | References 1. Escobar Z, et al. J Med Chem. 2016 May 26;59(10):4551-62. View Related Products by Target STAT |
| Molecular Formula | C17H25NO6S |
|---|---|
| Molecular Weight | 371.448 |