GPA 512
Modify Date: 2025-12-01 17:49:57
GPA 512 structure
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Common Name | GPA 512 | ||
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| CAS Number | 1808115-35-6 | Molecular Weight | 371.448 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C17H25NO6S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of GPA 512The orally bioavailable prodrug of Galiellalactone, a direct inhibitor of STAT3, prevents the transcription of STAT3 regulated genes; increases the plasma exposure of the active parent compound 20-fold compared to Galiellalactone; significantly reduces tumor growth in DU145 xenograft tumors. |
| Name | GPA 512 |
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| Description | The orally bioavailable prodrug of Galiellalactone, a direct inhibitor of STAT3, prevents the transcription of STAT3 regulated genes; increases the plasma exposure of the active parent compound 20-fold compared to Galiellalactone; significantly reduces tumor growth in DU145 xenograft tumors. |
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| References | References 1. Escobar Z, et al. J Med Chem. 2016 May 26;59(10):4551-62. View Related Products by Target STAT |
| Molecular Formula | C17H25NO6S |
|---|---|
| Molecular Weight | 371.448 |