177945-45-8
177945-45-8 structure
- Name: E-5842 hydrochloride
- Chemical Name: E-5842 hydrochloride
- CAS Number: 177945-45-8
- Molecular Formula: C17H22ClFN4
- Molecular Weight: 336.839
- Create Date: 2020-01-11 11:24:55
- Modify Date: 2024-01-05 09:45:04
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E-5842 is a preferential sigma-1 receptor ligand, demonstrates potential atypical antipsychotic effects in vivo; increases phospholipase C (PLC) activity in the striatum and the hippocampus, increased levels of Fos in the medial prefrontal cortex and the nucleus accumbens in rat forebrain.
| Name | E-5842 hydrochloride |
|---|
| Description | E-5842 is a preferential sigma-1 receptor ligand, demonstrates potential atypical antipsychotic effects in vivo; increases phospholipase C (PLC) activity in the striatum and the hippocampus, increased levels of Fos in the medial prefrontal cortex and the nucleus accumbens in rat forebrain. |
|---|---|
| References | References 1. Sánchez-Arroyos R, et al. Eur J Pharmacol. 1999 Jul 28;378(1):31-7. 2. Romero G, et al. Neurosci Lett. 2000 Sep 1;290(3):189-92. 3. Guitart X, et al. Neuropsychopharmacology. 2000 Nov;23(5):539-46. 4. Guitart X, et al. Eur J Pharmacol. 1998 Dec 18;363(2-3):127-30. View Related Products by Target Sigma Receptor |
| Molecular Formula | C17H22ClFN4 |
|---|---|
| Molecular Weight | 336.839 |