E-5842 hydrochloride

Modify Date: 2024-01-05 09:45:04

E-5842 hydrochloride Structure
E-5842 hydrochloride structure
Common Name E-5842 hydrochloride
CAS Number 177945-45-8 Molecular Weight 336.839
Density N/A Boiling Point N/A
Molecular Formula C17H22ClFN4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of E-5842 hydrochloride


E-5842 is a preferential sigma-1 receptor ligand, demonstrates potential atypical antipsychotic effects in vivo; increases phospholipase C (PLC) activity in the striatum and the hippocampus, increased levels of Fos in the medial prefrontal cortex and the nucleus accumbens in rat forebrain.

 Names

Name E-5842 hydrochloride

 E-5842 hydrochloride Biological Activity

Description E-5842 is a preferential sigma-1 receptor ligand, demonstrates potential atypical antipsychotic effects in vivo; increases phospholipase C (PLC) activity in the striatum and the hippocampus, increased levels of Fos in the medial prefrontal cortex and the nucleus accumbens in rat forebrain.
References References 1. Sánchez-Arroyos R, et al. Eur J Pharmacol. 1999 Jul 28;378(1):31-7. 2. Romero G, et al. Neurosci Lett. 2000 Sep 1;290(3):189-92. 3. Guitart X, et al. Neuropsychopharmacology. 2000 Nov;23(5):539-46. 4. Guitart X, et al. Eur J Pharmacol. 1998 Dec 18;363(2-3):127-30. View Related Products by Target Sigma Receptor

 Chemical & Physical Properties

Molecular Formula C17H22ClFN4
Molecular Weight 336.839
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