1531586-58-9
1531586-58-9 structure
- Name: AD-35
- Chemical Name: AD-35
- CAS Number: 1531586-58-9
- Molecular Formula: C24H27N3O3
- Molecular Weight: 405.498
- Create Date: 2020-01-12 23:37:21
- Modify Date: 2024-01-11 10:17:05
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A donepezil analog that can moderately inhibit acetylcholinesterase and metal-induced Aβ aggregation in vitro and shows disassembly of Aβ aggregates; markedly attenuates Aβ25-35 injection-induced astrocyte activation, pro-inflammatory cytokines TNF-α and IL-1β release, and memory deficits in vivo; orally active.
| Name | AD-35 |
|---|
| Description | A donepezil analog that can moderately inhibit acetylcholinesterase and metal-induced Aβ aggregation in vitro and shows disassembly of Aβ aggregates; markedly attenuates Aβ25-35 injection-induced astrocyte activation, pro-inflammatory cytokines TNF-α and IL-1β release, and memory deficits in vivo; orally active. |
|---|---|
| References | References 1. Li L, et al. J Alzheimers Dis. 2017;56(4):1403-1417. View Related Products by Target Acetylcholinesterase (AChE) |
| Molecular Formula | C24H27N3O3 |
|---|---|
| Molecular Weight | 405.498 |