AD-35
Modify Date: 2025-08-25 21:23:39
AD-35 structure
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Common Name | AD-35 | ||
|---|---|---|---|---|
| CAS Number | 1531586-58-9 | Molecular Weight | 405.498 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C24H27N3O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of AD-35A donepezil analog that can moderately inhibit acetylcholinesterase and metal-induced Aβ aggregation in vitro and shows disassembly of Aβ aggregates; markedly attenuates Aβ25-35 injection-induced astrocyte activation, pro-inflammatory cytokines TNF-α and IL-1β release, and memory deficits in vivo; orally active. |
| Name | AD-35 |
|---|
| Description | A donepezil analog that can moderately inhibit acetylcholinesterase and metal-induced Aβ aggregation in vitro and shows disassembly of Aβ aggregates; markedly attenuates Aβ25-35 injection-induced astrocyte activation, pro-inflammatory cytokines TNF-α and IL-1β release, and memory deficits in vivo; orally active. |
|---|---|
| References | References 1. Li L, et al. J Alzheimers Dis. 2017;56(4):1403-1417. View Related Products by Target Acetylcholinesterase (AChE) |
| Molecular Formula | C24H27N3O3 |
|---|---|
| Molecular Weight | 405.498 |
| InChIKey | SJXBQKLTADWYTC-UHFFFAOYSA-N |
| SMILES | O=C1c2cc3c(cc2C2(CC2)N1CCC1CCN(Cc2ccccn2)CC1)OCO3 |