1494619-28-1
1494619-28-1 structure
- Name: SINCRO
- Chemical Name: SINCRO
- CAS Number: 1494619-28-1
- Molecular Formula: C30H44N6O
- Molecular Weight: 504.723
- Create Date: 2020-01-11 19:01:50
- Modify Date: 2024-09-16 17:44:19
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SINCRO is a novel anti-cancer compound that can activate the cytosolic DNA-sensing STING signaling pathway leading to the induction of type I interferon (IFN) genes; SINCRO (STING-mediated interferon-inducing and cytotoxic reagent, original) shows a STING-independent cytotoxic activity against cancer cells, SINCRO does not evoke DNA double-strand break or caspase-3 cleavage, induces cell death in a manner different from conventional apoptosis-inducing pathways; significantly attenuates in vivo tumor growth by both type I IFN-dependent and independent mechanisms.
| Name | SINCRO |
|---|
| Description | SINCRO is a novel anti-cancer compound that can activate the cytosolic DNA-sensing STING signaling pathway leading to the induction of type I interferon (IFN) genes; SINCRO (STING-mediated interferon-inducing and cytotoxic reagent, original) shows a STING-independent cytotoxic activity against cancer cells, SINCRO does not evoke DNA double-strand break or caspase-3 cleavage, induces cell death in a manner different from conventional apoptosis-inducing pathways; significantly attenuates in vivo tumor growth by both type I IFN-dependent and independent mechanisms. |
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| References | References 1. Kimura Y, et al. Cancer Sci. 2018 Jul 7. doi: 10.1111/cas.13726. View Related Products by Target STING |
| Molecular Formula | C30H44N6O |
|---|---|
| Molecular Weight | 504.723 |