SINCRO
Modify Date: 2024-09-16 17:44:19
SINCRO structure
|
Common Name | SINCRO | ||
|---|---|---|---|---|
| CAS Number | 1494619-28-1 | Molecular Weight | 504.723 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C30H44N6O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of SINCROSINCRO is a novel anti-cancer compound that can activate the cytosolic DNA-sensing STING signaling pathway leading to the induction of type I interferon (IFN) genes; SINCRO (STING-mediated interferon-inducing and cytotoxic reagent, original) shows a STING-independent cytotoxic activity against cancer cells, SINCRO does not evoke DNA double-strand break or caspase-3 cleavage, induces cell death in a manner different from conventional apoptosis-inducing pathways; significantly attenuates in vivo tumor growth by both type I IFN-dependent and independent mechanisms. |
| Name | SINCRO |
|---|
| Description | SINCRO is a novel anti-cancer compound that can activate the cytosolic DNA-sensing STING signaling pathway leading to the induction of type I interferon (IFN) genes; SINCRO (STING-mediated interferon-inducing and cytotoxic reagent, original) shows a STING-independent cytotoxic activity against cancer cells, SINCRO does not evoke DNA double-strand break or caspase-3 cleavage, induces cell death in a manner different from conventional apoptosis-inducing pathways; significantly attenuates in vivo tumor growth by both type I IFN-dependent and independent mechanisms. |
|---|---|
| References | References 1. Kimura Y, et al. Cancer Sci. 2018 Jul 7. doi: 10.1111/cas.13726. View Related Products by Target STING |
| Molecular Formula | C30H44N6O |
|---|---|
| Molecular Weight | 504.723 |