935868-50-1
935868-50-1 structure
- Name: MK-1832
- Chemical Name: MK-1832
- CAS Number: 935868-50-1
- Molecular Formula: C23H17Cl2N3O
- Molecular Weight: 422.309
- Create Date: 2020-01-11 18:34:49
- Modify Date: 2024-09-27 00:46:15
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MK-1832 is a potent, selective Kv1.5 inhibitor with IC50 of 86 nM, exhibits improved selectivity for IKur over IKs (>3000-fold) compares with MK-0448 (70-fold), also exhibits an improved preclinical pharmacokinetic profile.
| Name | MK-1832 |
|---|
| Description | MK-1832 is a potent, selective Kv1.5 inhibitor with IC50 of 86 nM, exhibits improved selectivity for IKur over IKs (>3000-fold) compares with MK-0448 (70-fold), also exhibits an improved preclinical pharmacokinetic profile. |
|---|---|
| References | References 1. Wolkenberg SE, et al. Bioorg Med Chem Lett. 2017 Feb 15;27(4):1062-1069. View Related Products by Target Potassium Channel |
| Molecular Formula | C23H17Cl2N3O |
|---|---|
| Molecular Weight | 422.309 |