2376577-06-7
2376577-06-7 structure
- Name: M2N12
- Chemical Name: M2N12
- CAS Number: 2376577-06-7
- Molecular Formula: C20H16ClN5O2
- Molecular Weight: 393.83
- Catalog: Signaling Pathways Cell Cycle/DNA Damage CDK
- Create Date: 2019-12-08 12:49:19
- Modify Date: 2024-01-05 23:12:21
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M2N12 is a potent and highly selective cell division cycle 25C protein phosphatase (Cdc25C) inhibitor with an IC50 value of 0.09 μM. M2N12 also has promising activity against Cdc25A and Cdc25B with IC50 values of 0.53 μM and 1.39 μM. Anti-tumor activity[1].
| Name | M2N12 |
|---|
| Description | M2N12 is a potent and highly selective cell division cycle 25C protein phosphatase (Cdc25C) inhibitor with an IC50 value of 0.09 μM. M2N12 also has promising activity against Cdc25A and Cdc25B with IC50 values of 0.53 μM and 1.39 μM. Anti-tumor activity[1]. |
|---|---|
| Related Catalog | |
| In Vitro | M2N12 (0-20 μM; 72 hours) has cytotoxic activity against five tumor cell lines and a normal cell line including A-549, MDA-MB-231, KB, KB-VIN, MCF-7 and HBE (IC50=3.92 μM, 4.63 μM, 5.05 μM, 6.81 μM, 4.71 μM and 6.00 μM, respectively)[1]. |
| References |
| Molecular Formula | C20H16ClN5O2 |
|---|---|
| Molecular Weight | 393.83 |