2326007-49-0
2326007-49-0 structure
- Name: IV-23
- Chemical Name: IV-23
- CAS Number: 2326007-49-0
- Molecular Formula: C18H18BrNO4
- Molecular Weight: 392.24
- Catalog: Signaling Pathways Apoptosis Apoptosis
- Create Date: 2019-10-06 18:08:58
- Modify Date: 2024-01-03 15:38:58
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IV-23 (Compound 20) is a potent Noxa mediated apoptosis inducer, and it is a promising anticancer agent with potential. IV-23 inhibits cell growths in vitro and in vivo, reduces colony formation, arrests cell cycle at M phase, and induces esophageal squamous cell carcinoma (ESCC)[1].
| Name | IV-23 |
|---|
| Description | IV-23 (Compound 20) is a potent Noxa mediated apoptosis inducer, and it is a promising anticancer agent with potential. IV-23 inhibits cell growths in vitro and in vivo, reduces colony formation, arrests cell cycle at M phase, and induces esophageal squamous cell carcinoma (ESCC)[1]. |
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| Related Catalog | |
| In Vitro | IV-23 (Compound 20) shows a strong inhibition against the ESCCs in a concentration depend manner, the IC50 values against the Kyse30 and Kyse450 cell lines were all less than 2 μM, presented in a dose-dependent manner. IV-23 triggeres caspases related apoptosis in ESCC cells[1]. IV-23 induces G2/M phase arrest[1]. |
| References |
| Molecular Formula | C18H18BrNO4 |
|---|---|
| Molecular Weight | 392.24 |